Technical Guides

Fmoc solid-phase peptide synthesis: the reagents you need, step by step – KUGAKI technical guide cover21 Oct 2026 Fmoc solid-phase peptide synthesis: the reagents you need, step by step Resins, protected amino acids, coupling reagents and orthogonal protecting groups for Fmoc SPPS, explained in the order you use them, with links to the building blocks we stock. Building blocks for medicinal chemistry, click chemistry and bioconjugation – KUGAKI technical guide cover20 Oct 2026 Building blocks for medicinal chemistry, click chemistry and bioconjugation Boronic acids for Suzuki coupling, heterocycles for scaffolds, and the azide, alkyne, NHS-ester and maleimide handles used to link molecules together. Choosing a biological buffer: HEPES, Tris, MES, MOPS and PIPES compared – KUGAKI technical guide cover19 Oct 2026 Choosing a biological buffer: HEPES, Tris, MES, MOPS and PIPES compared Match the buffer to your working pH, temperature and assay. A practical comparison of HEPES, Tris, MES, MOPS and PIPES, with the pitfalls that cause drifting pH and failed assays.